My sister 25yr, hypothyroidism and thyroid scanning reveals diffuse goiter. Can somebody explain me everything?

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age 25yr
Continuous weight gain
hypothyroidism, T4= .04 and TSH= >100
thyroid scan shows diffuse goiter with no nodules.

I want to know, is it really a serious matter. And regarding treatment? Does it lead to surgery? Is it curable?

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