Metabolism of Dietary Cholesterol?

If you eat say meat, you are consuming cholesterol. But what happens to it during digestion? What is it metabolized into? I know that cholesterol is useful for lipid (fat ) digestion. So what happens in the case of "0 cholesterol" food. Does the body synthesize its own cholesterol? If so, what is it synthesized from? How does eating "0 cholesterol" food corelate to eating healthy?

One comment

  • wiseowl_00

    Any cholesterol you consume, along with lipids, is packed into a lipoprotein called a chylomicron in the small intestine. The chylomicron travels via the bloodstream and looses the lipids to cells for energy or storage, becoming a chylomicron remnant. The chylomicrom remnant is absorbed by the liver, thus delivering dietary cholesterol to the liver.

    In the liver , lipids produced by the liver and cholesterol is packed into a Very Low Density Lipoprotein. The VLDL looses the lipids to cells in the same way as a chlyomicron, eventually becoming an LDL. If cells require cholesterol they will have a receptor enabling the LDL to be absorbed into the cell. The cholesterol can then be utilised by the cell.

    When cholesterol is being transported or stored it is in the form of Cholesteryl Esters, that is it is combined with a fatty acid. It has the fatty acid removed so as to become free cholesterol again when it is utilised.

    The liver synthesises most of the body’s needs for cholesterol. Reducing dietary cholesterol will only result in increased production by the liver. This is synthesised from Acetyl CoA. For more info on synthesis
    Eating 0 cholesterol just means more work for you liver

Leave a Reply

Your email address will not be published.