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Is cholesterol another word for plaque?
"Cholesterol" often refers to the amount of cholesterol floating around in your blood. It’s made my your liver and lots of foods have cholesterol.
"Plaque" often refers to a buildup of fatty gunk on the inside of arteries. Most of the time, people are most concerned about plaque buildup in the heart.
Having high blood cholesterol increases the chance of having significant plaques and therefore increases the chance of heart attacks in the future.
So they’re not that same thing, but closely related.
Cholesterol is a waxy steroid metabolite found in the cell membranes and transported in the blood plasma of all animals.
Atheromatous plaque, a buildup of white blood cell (sometimes termed fatty, despite absence of adipocytes) deposits within the wall of an artery
Cholesterol and plaque are most definitely not the same thing but there are related. The higher the total – and most especially the LDL – cholesterol the greater the amount of plaque in arteries. No one is absolutely certain how this process works but the following is a generally accepted summary. Small dense particles of LDL cholesterol penetrate the endothelial lining of arteries. Monocytes phagocytize (consume) this LDL cholesterol and these cells become tissue specific macrophages known as foam cells. This causes an inflammatory response. This also causes a monoclonal proliferation of smooth muscle cells. If this process is not reversed a so-called ‘fatty streak’ progress to arterial plaque which may eventually narrow the artery. When these plaques develop a calcified ‘cap’ they are most prone to ‘rupture’ or ‘fracture’ resulting in a blood clot and arterial occlusion. The process of plaque formation is considerably more complex than this and remains incompletely understood although the above is a fairly good summary. If I may be of further assistance please let me know. I wish you the very best of health and in all things may God bless.
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